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ONTOLOGY REPORT - ANNOTATIONS


Term:actin filament capping
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Accession:GO:0051693 term browser browse the term
Definition:The binding of a protein or protein complex to the end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.
Synonyms:related_synonym: F-actin capping activity;   actin capping activity


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actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AVIL advillin involved_in IEA UniProt GO_REF:0000043 NCBI chr11:53,708,969...53,732,219
Ensembl chr11:53,707,566...53,728,894
JBrowse link
G CAPZA1 capping actin protein of muscle Z-line subunit alpha 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr20:20,968,348...21,017,256
Ensembl chr20:20,969,828...20,991,971
JBrowse link
G CAPZA2 capping actin protein of muscle Z-line subunit alpha 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr21:85,543,297...85,598,346
Ensembl chr21:85,543,271...85,601,370
JBrowse link
G CAPZA3 capping actin protein of muscle Z-line subunit alpha 3 involved_in IEA UniProt GO_REF:0000043 NCBI chr11:18,587,809...18,588,885
Ensembl chr11:18,587,966...18,588,865
JBrowse link
G CAPZB capping actin protein of muscle Z-line subunit beta involved_in IEA UniProt GO_REF:0000043 NCBI chr20:113,062,077...113,207,983
Ensembl chr20:113,062,192...113,210,430
JBrowse link
G GSN gelsolin involved_in IEA Ensembl
UniProt
GO_REF:0000043 GO_REF:0000107 NCBI chr12:18,253,079...18,317,285
Ensembl chr12:18,253,324...18,285,938
JBrowse link
G MYH9 myosin heavy chain 9 NOT|involved_in ISO (MGI:5619440|PMID:23325791) UniProt PMID:23325791 MGI:5619440 NCBI chr19:18,985,709...19,093,304
Ensembl chr19:18,986,598...19,052,671
JBrowse link
G RDX radixin involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:101,554,640...101,647,765
Ensembl chr 1:101,554,334...101,623,093
JBrowse link
G SCIN scinderin involved_in ISO (PMID:19666531) UniProt PMID:19666531 NCBI chr21:45,453,034...45,537,733
Ensembl chr21:45,452,659...45,537,323
JBrowse link
G SPTA1 spectrin alpha, erythrocytic 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr20:5,238,246...5,314,204
Ensembl chr20:5,238,447...5,313,887
JBrowse link
G SPTAN1 spectrin alpha, non-erythrocytic 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr12:9,503,752...9,585,297
Ensembl chr12:9,503,367...9,585,268
JBrowse link
G SPTB spectrin beta, erythrocytic involved_in IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr24:41,957,438...42,038,522
Ensembl chr24:41,978,595...42,038,516
JBrowse link
G SPTBN1 spectrin beta, non-erythrocytic 1 involved_in IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr14:52,266,197...52,487,111
Ensembl chr14:52,262,416...52,487,112
JBrowse link
G SPTBN2 spectrin beta, non-erythrocytic 2 involved_in IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr 1:7,543,035...7,588,125
Ensembl chr 1:7,556,953...7,590,720
JBrowse link
G SPTBN4 spectrin beta, non-erythrocytic 4 involved_in IEA UniProt GO_REF:0000043 NCBI chr 6:34,926,413...35,036,611
Ensembl chr 6:34,930,519...35,035,719
JBrowse link
G SPTBN5 spectrin beta, non-erythrocytic 5 involved_in IEA UniProt GO_REF:0000043 NCBI chr26:41,090,023...41,137,645
Ensembl chr26:41,091,478...41,135,932
JBrowse link
G TPM1 tropomyosin 1 ISO RGD PMID:15779917 RGD:1600523 NCBI chr26:20,458,287...20,487,387
Ensembl chr26:20,466,037...20,487,135
JBrowse link
G VIL1 villin 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr10:104,311,048...104,350,846
Ensembl chr10:104,320,074...104,347,289
JBrowse link
G VILL villin like involved_in IEA UniProt GO_REF:0000043 NCBI chr15:1,395,763...1,412,352
Ensembl chr15:1,395,776...1,409,351
JBrowse link
barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADD1 adducin 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr27:45,811,611...45,901,277
Ensembl chr27:45,813,496...45,900,778
JBrowse link
G ADD2 adducin 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:36,343,978...36,450,685
Ensembl chr14:36,344,022...36,449,315
JBrowse link
G ADD3 adducin 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:102,930,270...103,056,558
Ensembl chr 9:103,010,713...103,057,101
JBrowse link
G AVIL advillin involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:53,708,969...53,732,219
Ensembl chr11:53,707,566...53,728,894
JBrowse link
G CAPZA1 capping actin protein of muscle Z-line subunit alpha 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17656356) InterPro
MGI
TreeGrafter
UniProt
PMID:17656356 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chr20:20,968,348...21,017,256
Ensembl chr20:20,969,828...20,991,971
JBrowse link
G CAPZA2 capping actin protein of muscle Z-line subunit alpha 2 involved_in IEA InterPro
TreeGrafter
UniProt
GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chr21:85,543,297...85,598,346
Ensembl chr21:85,543,271...85,601,370
JBrowse link
G CAPZA3 capping actin protein of muscle Z-line subunit alpha 3 involved_in IEA InterPro
TreeGrafter
UniProt
GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chr11:18,587,809...18,588,885
Ensembl chr11:18,587,966...18,588,865
JBrowse link
G CAPZB capping actin protein of muscle Z-line subunit beta involved_in IEA InterPro
TreeGrafter
UniProt
GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chr20:113,062,077...113,207,983
Ensembl chr20:113,062,192...113,210,430
JBrowse link
G DBNL drebrin like NOT|acts_upstream_of_or_within ISO (PMID:10637315) MGI PMID:10637315 NCBI chr21:14,610,196...14,627,363
Ensembl chr21:14,608,571...14,627,321
JBrowse link
G EPS8 EGFR pathway substrate 8, signaling adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:15,522,761...15,691,343
Ensembl chr11:15,522,616...15,691,133
JBrowse link
G FLII FLII actin remodeling protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:17,285,400...17,300,210
Ensembl chr16:17,285,724...17,300,041
JBrowse link
G GSN gelsolin involved_in IEA UniProt
TreeGrafter
GO_REF:0000104 GO_REF:0000118 NCBI chr12:18,253,079...18,317,285
Ensembl chr12:18,253,324...18,285,938
JBrowse link
G LOC103219957 macrophage-capping protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:21,742,163...21,761,462
Ensembl chr14:21,746,044...21,761,322
JBrowse link
G LOC103227720 twinfilin-2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr22:13,581,102...13,598,830
Ensembl chr22:13,589,034...13,598,752
Ensembl chr22:13,589,034...13,598,752
JBrowse link
G LOC103238065 supervillin-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:29,072,613...29,256,563
Ensembl chr 9:29,072,322...29,164,759
JBrowse link
G LOC119627284 macrophage-capping protein-like involved_in IEA TreeGrafter GO_REF:0000118
G RDX radixin ISO RGD PMID:2500445 RGD:8693627 NCBI chr 1:101,554,640...101,647,765
Ensembl chr 1:101,554,334...101,623,093
JBrowse link
G SCIN scinderin involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:45,453,034...45,537,733
Ensembl chr21:45,452,659...45,537,323
JBrowse link
G TWF1 twinfilin actin binding protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:40,000,458...40,019,490
Ensembl chr11:39,999,926...40,019,502
JBrowse link
G VIL1 villin 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:104,311,048...104,350,846
Ensembl chr10:104,320,074...104,347,289
JBrowse link
G VILL villin like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr15:1,395,763...1,412,352
Ensembl chr15:1,395,776...1,409,351
JBrowse link
negative regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARMIL1 capping protein regulator and myosin 1 linker 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:46,637,416...46,979,061
Ensembl chr17:46,635,199...46,978,932
JBrowse link
G CARMIL2 capping protein regulator and myosin 1 linker 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:59,787,069...59,801,615
Ensembl chr 5:59,787,120...59,801,122
JBrowse link
G CRACD capping protein inhibiting regulator of actin dynamics involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 7:12,293,366...12,570,793
Ensembl chr 7:12,296,214...12,325,965
JBrowse link
pointed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LMOD1 leiomodin 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr25:27,460,230...27,511,667
Ensembl chr25:27,460,460...27,511,024
JBrowse link
G LMOD2 leiomodin 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr21:92,454,067...92,462,904
Ensembl chr21:92,454,438...92,462,958
JBrowse link
G LMOD3 leiomodin 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr22:30,132,993...30,149,769
Ensembl chr22:30,135,153...30,148,740
JBrowse link
G TMOD1 tropomodulin 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr12:41,808,594...41,899,713
Ensembl chr12:41,811,036...41,877,357
JBrowse link
G TMOD2 tropomodulin 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr26:31,560,112...31,624,967
Ensembl chr26:31,568,024...31,624,905
JBrowse link
G TMOD3 tropomodulin 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr26:31,470,138...31,549,615
Ensembl chr26:31,471,362...31,549,571
JBrowse link
G TMOD4 tropomodulin 4 involved_in IEA InterPro GO_REF:0000002 NCBI chr20:12,513,935...12,519,497
Ensembl chr20:12,515,429...12,519,402
JBrowse link
positive regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARPC2 actin related protein 2/3 complex subunit 2 ISO RGD PMID:15252126 RGD:2306210 NCBI chr10:104,098,275...104,144,043
Ensembl chr10:104,098,402...104,135,791
JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:23704350 RGD:11570555 NCBI chr 1:8,408,560...8,410,564 JBrowse link
regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD52 ankyrin repeat domain 52 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:52,191,840...52,216,505
Ensembl chr11:52,197,178...52,216,362
JBrowse link
G MTPN myotrophin involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:104,605,924...104,657,664
Ensembl chr21:104,605,592...104,657,866
JBrowse link
G TNKS tankyrase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:9,300,234...9,524,350
Ensembl chr 8:9,305,872...9,524,104
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16925
    cellular process 15887
      negative regulation of cellular process 5149
        negative regulation of cellular component organization 795
          negative regulation of supramolecular fiber organization 184
            negative regulation of actin filament depolymerization 51
              actin filament capping 45
                barbed-end actin filament capping + 29
                pointed-end actin filament capping 7
Path 2
Term Annotations click to browse term
  biological_process 16925
    cellular process 15887
      cellular component organization or biogenesis 6765
        cellular component organization 6524
          organelle organization 3662
            cytoskeleton organization 1524
              actin cytoskeleton organization 729
                actin filament organization 470
                  actin polymerization or depolymerization 211
                    regulation of actin polymerization or depolymerization 173
                      regulation of actin filament depolymerization 60
                        negative regulation of actin filament depolymerization 51
                          actin filament capping 45
                            barbed-end actin filament capping + 29
                            pointed-end actin filament capping 7
paths to the root